If you love Mother of Mine then you might also love My Golden Life ! The two of them are similar in many ways : it shows the struggle of a family with the love-hatred relationship between sisters and mother's sacrifices to raise her children. It depicts the different aspects of every characters and the romance between the two main characters is also similar to the romance between Kang Miri and Han Taeju in Mother of Mine as it's about a man madly in love with a woman who wants to preserve her family and her work rather than start a relationship. As their family's situation seems to do nothing but getting them apart their love for eachothers can only grow stronger. Finally these two dramas are about the same number of episodes (about 50 episodes of 1hour).
Habitually I'm not very fond of dramas with a lot of episodes but these two were the exceptions, so don't miss My Golden Life out !!