Ronin Samurai aka Lone Wolf with Cub fights against shadow Yagyu Ninja attacks after they frame him against the Shogun!

Both deal with Samurai versus Ninjas! Children are raised to be demon wearing mask ninjas, but less then half survive the brutal training!

Both have samurai vs. Ninjas! Both Lone Wolf and Azumi fight against a whole army of Samurai! Do they win?

Lady katana assassin seeks vengeance against evil clan but they hire lone wolf to stop her!..
.... ..........

Lone wolf and cub face off against Yagyu shadow ninjas and beats them so the leader of the yagyu seek help from a group of lady ninjas!

Lone wolf and cub face off against a tattooed s lady assassin!,...............................,..........

Both about a lady assassin! Azumi is trained since an orphaned young child to be a master ninja but something goes wrong on het 1st mission and her whole team is killed!

Azuni is orphaned as a child but taken in by the master who traines her and othet children to be ninja assassins!

Both about a female assassin based on a manga! And both are orphans!
But Azumi is trained to be a ninja as a child!

Also Samurai vs. Ninjas!
Azumi is trained to be a ninja since a young child. Het 1st mission goes badly losing all her team except one so seeks revenge!

Ninjas vs samurai! Azumi is trained to be a ninja since she was a littke girl!
' Nuff said as Stan Lee would put it!

Azumi was also trained to be a ninja as a child! More than half the children died during training just like DemonSpies!